estimated number of people living with HIV in 2019
people were newly infected with HIV in 2019
people died of HIV-related causes in 2019
percentage of adults living with HIV received lifelong antiretroviral therapy (ART) in 2019*
*Worldwide, courtesy of WHO
While there's no cure for HIV, there are very effective treatments that enable most people with the virus to live a long and healthy life
The world has made significant progress since the late 1990s, but HIV remains a major global public health issue. And like many other major health issues, it faces additional challenges during the COVID-19 pandemic.
HIV prevention, testing, treatment and care services are all being disrupted particularly in countries with fragile heath systems. The breakdown in essential HIV services due to COVID-19 is threatening lives. Any slowing down in provision of these services will leave many vulnerable populations at greater risk of HIV infection and AIDS-related deaths.
Nevertheless, all over the world, health workers and community representatives are doing their utmost to keep services going, adopting innovative ways to overcome disruptions in services caused by COVID-19.
Scanning electrio-1, (coloured pink), budding from a cultured lymphocyte
What are HIV and AIDS?
HIV- Human Immunodeficiency Virus
HIV attacks the body’s immune system gradually causing damage. Without treatment, the immune system will become too weak to fight off illness and infection.
There is currently no cure for HIV. But major advances in treatment mean that many people can lead long and healthy lives, although some may experience side effects from the treatment.
HIV is present in blood, genital fluids (semen, vaginal fluids and moisture in the rectum) and breast milk.
AIDS- Acquired Immune Deficiency Syndrome
AIDS is the term used to describe a stage of HIV infection when the body is too weak to fight off a range of diseases.
You cannot catch AIDS. HIV causes AIDS and it is HIV that can be passed on. Being diagnosed with AIDS means different things for different people.
Just because someone has AIDS does not mean they will die – but it is essential to have medical care and treatment.
The main ways HIV can be passed on
In the UK, most cases of HIV are caused by having sex with a person who has HIV without using a condom.
A person with HIV can pass the virus on to others even if they don't have any symptoms. People with HIV can pass the virus on more easily in the weeks following infection.
HIV treatment significantly reduces the risk of someone with HIV passing it on.
Most people diagnosed with HIV in the UK acquire the virus through unprotected vaginal or anal sex.
It may also be possible to catch HIV through unprotected oral sex, but the risk is much lower.
The risk is higher if:
- the person giving oral sex has mouth ulcers, sores or bleeding gums
- the person receiving oral sex has recently been infected with HIV and has a lot of the virus in their body, or another sexually transmitted infection
Other risk behaviours
Other ways of getting HIV include:
- sharing needles, syringes and other injecting equipment
- from mother to baby before or during birth or by breastfeeding
- sharing sex toys with someone infected with HIV
- healthcare workers accidentally pricking themselves with an infected needle, but this risk is extremely low
- blood transfusion – now very rare in the UK, but still a problem in developing countries
How HIV is transmitted
HIV isn't easily passed on from one person to another. The virus doesn't spread through the air like cold and flu viruses.
HIV lives in the blood and in some body fluids. To get HIV, one of these fluids from someone with HIV has to get into your blood.
The body fluids that contain enough HIV to infect someone are:
- vaginal fluids, including menstrual blood
- breast milk
- lining inside the anus
Other body fluids, like saliva, sweat or urine, don't contain enough of the virus to infect another person.
The main ways the virus enters the bloodstream are:
- by injecting into the bloodstream with needles or injecting equipment that's been shared with other people
- through the thin lining on or inside the anus, vagina and genitals
- through the thin lining of the mouth and eyes
- through cuts and sores in the skin
But there are ways of preventing HIV infection in all of these situations.
There are many effective ways to prevent or reduce the risk of HIV infection. Speak to your local sexual health clinic or a GP for further advice about the best way to reduce your risk.
HIV isn't passed on through:
- being bitten
- contact with unbroken, healthy skin
- being sneezed on
- sharing baths, towels or cutlery
- using the same toilets or swimming pools
- mouth-to-mouth resuscitation
- contact with animals or insects like mosquitoes
Symptoms of HIV
These vary from person to person, People can live with HIV for years before having any symptoms. The only way to be sure if you have HIV is to have an HIV test. You cannot tell from symptoms alone.
However, most people infected with HIV experience a short, flu-like illness that occurs 2-6 weeks after infection. After this, HIV may not cause any symptoms for several years.
It's estimated up to 80% of people who are infected with HIV experience this flu-like illness.
The most common symptoms are:
raised temperature (fever)
Other symptoms can include:
The symptoms usually last 1-2 weeks, but can be longer. They're a sign that your immune system is putting up a fight against the virus.
But having these symptoms does not necessarily mean you have the HIV virus. Remember: they're commonly caused by conditions other than HIV.
If you have several of these symptoms and think you've been at risk of HIV infection within the past few weeks, you should get an HIV test.
After the initial symptoms disappear, HIV may not cause any further symptoms for many years.
During this time, the virus continues to be active and causes progressive damage to your immune system.
This process can vary from person to person, but may take up to 10 years, during which you'll feel and appear well.
Once the immune system becomes severely damaged, symptoms can include:
serious life-threatening illnesses
Earlier diagnosis and treatment of HIV can prevent these problems.
Why take an HIV Test?
You should still take an HIV test if you may have been at risk at any time in the past, even if you do not experience any symptoms.
The sooner you’re diagnosed with HIV, the sooner you can start treatment.
Antiretroviral drugs(ARVs) will keep the virus under control by stopping it from reproducing itself. The goal is to keep levels of HIV so low that in tests the person has an undetectable viral load.
If someone with HIV is on effective treatment and has an undetectable viral load they cannot pass on HIV.
There are now many quick and convenient ways to test for HIV
HIV tests are available in lots of healthcare settings. This might be in a sexual health clinic, doctor’s surgery, hospital or private clinic, for example. In many countries, there are also places where you can be tested in your local community.
In the UK, you can get a free and confidential HIV test at any NHS sexual health or GUM (genito-urinary medicine) clinic.
These clinics are linked into specialist HIV services, and there will be support available to you if your result is positive.
An HIV test is the only way to know if you have HIV
Current treatment for HIV
Antiretroviral drugs cannot cure HIV but work by reducing the amount of HIV in the body so the immune system can work normally.
This doesn’t get rid of HIV completely, but with the right treatment and care, someone with HIV can expect to live a long and healthy life.
It is now recommended that everyone diagnosed with HIV starts treatment straight away.
Early diagnosis enables better treatment outcomes and reduces the risk of onward transmission.
HIV rapid test being administered
People diagnosed late have a much higher risk of developing complex health conditions including HIV -associated brain impairment.
If you test positive
If you're diagnosed with HIV, you'll have regular blood tests to monitor the progress of the HIV infection before starting treatment.
2 important blood tests are:
- HIV viral load test – a blood test that monitors the amount of HIV virus in your blood
- CD4 lymphocyte cell count – which measures how the HIV has affected your immune system
Treatment can be started at any point following your diagnosis, depending on your circumstances and in consultation with your HIV doctor.
Image by Tomasz Ryś
HIV is treated with antiretroviral medications, which work by stopping the virus replicating in the body. This allows the immune system to repair itself and prevent further damage.
A combination of HIV drugs is used because HIV can quickly adapt and become resistant.
Some HIV treatments have been combined into a single pill, known as a fixed dose combination, although these often cost more to prescribe.
Usually, people who have just been diagnosed with HIV take between 1 and 4 pills a day.
Different combinations of HIV medicines work for different people, so the medicine you take will be individual to you.
The amount of HIV virus in your blood (viral load) is measured to see how well treatment is working. Once it can no longer be measured it's known as undetectable. Most people taking daily HIV treatment reach an undetectable viral load within 6 months of starting treatment.
Many of the medicines used to treat HIV can interact with other medicines prescribed by your GP or bought over-the-counter.
These include some nasal sprays and inhalers, herbal remedies like St John's wort, as well as some recreational drugs. Always check with your HIV clinic staff or your GP before taking any other medicines.
PrEP and PEP
What is PrEP?
Pre-exposure prophylaxis (PrEP) is an HIV prevention strategy that uses antiretroviral drugs to protect people who do not have HIV but who are at high risk of contracting HIV.
To be effective, Prep must be taken regularly, as directed. It does not prevent other sexually transmitted infections.
What is PEP?
Post-exposure Prophylaxis (PEP) is a short-term treatment that stops HIV spreading through the body.
It must be taken within 72 hours of possible exposure to HIV.
HIV-Associated Brain Impairment (HAND)
Mildmay specialises in the treatment of HIV-Associated Neurocognitive Disorder, or HAND, impairment caused by HIV entering and affecting the brain.
This is a form of severe dementia which Mildmay is able to reverse in the majority of our patients, enabling them to return to some form of independent living.
People with HAND often display symptoms that are very similar to dementia, such as memory loss, confusion, loss of a sense of self, difficulty in walking, speaking or carrying out every day tasks.
Mildmay’s specialised treatment, care and rehabilitation includes highly skilled medical and nursing care, treatment, rehabilitation and a combined range of therapies.
HIV in the UK*London has the largest numbers of people living with HIV, but numbers are growing in every part of the UK.
GloballySub-Saharan Africa has the most serious HIV and AIDS epidemic in the world. In 2013, an estimated 24.7 million people were living with HIV, accounting for 71 per cent of the global total.
HIV Pregnancy and Birth**In the UK with the right treatment and care, 99 per cent of women living with HIV give birth to healthy babies without passing on HIV.
Mildmay is the first specialist unit aiming to provide pioneering step-down care* for the homeless population of London and the surrounding regions
With homelessness in London and other major cities across the UK increasing, there is urgent need for highly focused, specialist care of the sort that Mildmay Hospital provides.
Registered Charity no: 292058